KERATOCONUS

What is Keratoconus?

Keratoconus – which literally means “cone shaped cornea”, is a progressive, bilateral eye disease that that causes thinning and cone-like steepening of the cornea. In addition to the coning, Keratoconus can also cause an irregular cornea. The result of which leaves the patient with severely distorted vision accompanied by halos, glares and multiple images (ghosting) and light sensitivity. As it progresses, the result is severe vision impairment and can lead to functional blindness.

Classically thought to be rare disease, new research shows it’s much more in common that thought, impacting almost 1:400 people, an increase of 5x more than originally thought. However, prevalence rates around the world are significantly higher, and in some regions, studies show 1:21. It affects those primarily around 15-45 years of age, however the onset is most often in late teens to young adults. For more information about Keratoconus .. visit our links in Resources.

THE PROBLEM

Let's take a look at the problem.

The Keratoconic cornea is not only cone-shaped, but also mal-aligned and asymmetrical. There is a great deal of corneal irregularity and this is what causes the severe vision impairment.

For the patient, vision correction treatment has to address improving the symmetry of the cornea as well as re-alignment of the cone to the optical axis. And since each patient’s corneal biomechanics are different, a one size-fits all approach is not effective. The current vision correction treatments do not provide for a personalized approach for Keratoconus. The current treatment path is very much a trial and error of vision correction devices and/or surgical treatments, either standalone or in combination.

This becomes a frustrating, lengthy, costly process for the patient. The eye doctor struggles with clinical response predictability due to the unique challenges of each patient’s cornea. These are just some of the reasons why Keratoconus remains a high, unmet, clinical need in ophthalmology.

There is currently no treatment that offers a patient-centric solution and addresses the multiple challenges of a Keratoconic cornea to provide superior clinical outcomes.

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TECHNOLOGY

“It's not new that architecture can profoundly affect a place, sometimes transform it. Architecture and any art can transform a person, even save someone” Frank Gehry, world-renowned architect

The World’s First Patient-Centric Corneal Re-Shaping Platform.

Not every Keratoconic cornea is the same, each has different corneal characteristics or specific corneal topography. Differences in the cone shape, location and irregularity impact each patient in a unique manner. Therefore, like current technologies, a one-size fits all approach has significant limitations. MAG Optic’s intra-corneal implant allows for a specific and directed biomechanical force to reshape the cornea in a manner unique to that patient.

Our technology is transforming an irregular cornea to a regular cornea. This approach has yielded very promising results. Our data demonstrates, that not only have we achieved alignment to the visual axis, but also, significant improvement in the regularity of the central cornea. This allows for vastly improved vision for the patient in visual acuity and a reduction in halos, glares, and ghosting images.

Additionally, the technology has demonstrated effective results in Presbyopia (age-related loss of near vision). We anticipate using the technology to address other large refractive error markets as well.

Quite simply – for the surgeon, we are transforming the cornea. For the patient, we are transforming lives.

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MAG OPTICS: ARCHITECTS OF VISION

``Make no small plans, they have no magic to stir men’s blood” Daniel Burnham. world-famous American architect and planner

We are MAG Optics, architects of vision and we are re-engineering vision.

The eye is one of the most complex organs in our body with over 2 million moving parts. The cornea, the most outerpart of the eye, is transparent, complex and responsible for almost 75% of human optical power. Its main job is to help bend (refract) and focus incoming light. Therefore, any abnormalities in the corneal shape will cause refractive errors and impact vision. Its structure, shape, biomechanics are instrumental in how we visualize.

MAG Optics is an ophthalmic device innovator and is developing the world’s first patient-centric corneal re-shaping platform. The intra-corneal implant is used to treat Keratoconus, a progressive, degenerative eye disease that causes severe visual impairment as well as other visual conditions such as Presbyopia (age-related loss of near vision).

OUR TEAM

“I’ve always felt if you know what you’re going to do in advance, then you won’t do it. Your creativity starts whether you’re curious or not.” Frank Gehry

Hakam Ghabra
Dr. Hakam Ghabra
Co-founder, CSO
Geeta Singh
Geeta Singh
Co-founder, CEO
Marwan Ghabra
Dr. Marwan Ghabra
Co-founder, Inventor, Scientific Board
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RESOURCES

Some helpful links

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RT @KeratoconusGRP: When you have #keratoconus and someone asks why you don't use glasses: https://t.co/q08urzU0Pq
19 September 2018
RT @patsdudecanbake: @jainajgd This is bananas!!! I was recently diagnosed with Keratoconus --- I wonder if I were misdiagnosed and it coul…
13 September 2018
RT @Tender_roni_: Never take sight for granted. I used to hate wearing glasses now i wish I could have the option 😓#keratoconus #keratoconu…
13 September 2018
RT @labcentral: @labcentral learns how to speak like a Ted-Worthy Leader, thanks to our sponsor @JNJNews @JLABS @BioSammy @johnbates & his…
12 September 2018
RT @MagOptics: Carrying the @UMassM2D2 @jlabs banner ! #RESIBOS18 #magoptics #ophthalmology #medtech #keratoconus https://t.co/bILNRqmD5F
06 September 2018
Carrying the @UMassM2D2 @jlabs banner ! #RESIBOS18 #magoptics #ophthalmology #medtech #keratoconus https://t.co/bILNRqmD5F
06 September 2018
See you there! https://t.co/Ogi7tSERBV
05 September 2018
Looking forward to presenting at Techhub challenge #RESIBOS18 on Sept 6 in #boston #MagOptics #ophthalmology… https://t.co/msC6dGd3zb
04 September 2018
We're excited to be presenting at #RESIBOS18 #techhubinnovationchallenge #MagOptics #reengineeringvision… https://t.co/owO7Le12XN
04 September 2018
RT @OphthoMag: ?Remember when your parents told you that you can do anything? They were right? Read Bonnie An Henderson?s advice to aspirin…
03 September 2018

CONTACT MAG OPTICS INC.

please feel free to contact us for inquiries

Please feel free to contact us for inquiries

Resident Office: M2D2 at JLabs, 110 Canal Street, Lowell, MA 01852

Mailing Address: 3621 W. Wrightwood Avenue, Chicago, IL 60647

Get in touch: info@magoptics.com

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